| Season: | 2010–11 |
| Winners: | Octavio Pilotes Posada |
| Relegated: | Universidad León Ademar, Grupo Pinta Torrelavega & HV Ingenieros Almoradí |
| Matches: | 240 |
| Total Goals: | 13751 |
| Nextseason: | 2011–12 |
The 2010–11 season of the División de Plata de Balonmano is the 17th season of second-tier handball in Spain.
The promotion playoffs will grant a seat in Liga ASOBAL for 2011–12 season.