| Diso | |
| Official Name: | Comune di Diso |
| Shield Alt: | Coat of arms of Diso |
| Pushpin Label Position: | left |
| Coordinates: | 40.0167°N 42°W |
| Region: | Apulia |
| Province: | (LE) |
| Frazioni: | Marittima, Marina di Marittima |
| Mayor: | Antonella Carrozzo |
| Area Total Km2: | 11.42 |
| Population Footnotes: | [1] |
| Population Total: | 2960 |
| Population As Of: | 31 July 2017 |
| Population Demonym: | Disini |
| Elevation M: | 99 |
| Saint: | St. Philip and St. James |
| Day: | 1 May |
| Postal Code: | 73030 |
| Area Code: | 0836 |
Diso (Salentino: Sicilian: Disu;) is a town and comune in the province of Lecce in the Apulia region of south-east Italy.
It has existed since the early 11th century, and features several churches, buildings and squares.