| Jurisdiction: | Diocese |
| Santo Ângelo | |
| Latin: | Dioecesis Angelopolitana |
| Country: | Brazil |
| Province: | Santa Maria |
| Rite: | Latin Rite |
| Established: | 22 May 1961 (years ago) |
| Cathedral: | Guardian Angel Cathedral |
| Area Km2: | 16776 |
| Population: | 508,000 |
| Population As Of: | 2004 |
| Catholics: | 389,000 |
| Catholics Percent: | 76.6 |
| Map: | File:Diocese de Santo Ângelo.svg |
| Website: | www.diocesedesantoangelo.org.br |
The Roman Catholic Diocese of Santo Ângelo (Latin: Dioecesis Angelopolitana) is a diocese located in the city of Santo Ângelo in the ecclesiastical province of Santa Maria in Brazil.