| Jurisdiction: | Diocese |
| Ciego de Avila | |
| Latin: | Dioecesis Caeci Abulensis |
| Country: |  Cuba |
| Metropolitan: | Ciego de Avila |
| Province: | Province of Camagüey |
| Area Km2: | 7,887 |
| Population: | 452,100 |
| Population As Of: | 2006 |
| Catholics: | 186,900 |
| Catholics Percent: | 41.3 |
| Parishes: | 4 |
| Denomination: | Roman Catholic |
| Rite: | Latin Rite |
| Established: | 10 December 1912 (years ago) |
| Cathedral: | Catedral de San Eugenio de la Palma |
| Bishop Title: | Bishop |
| Emeritus Bishops: | Mario Eusebio Mestril Vega |
The Roman Catholic Diocese of Ciego de Avila is a suffragan Latin diocese of the Metropolitan Archdiocese of Camagüey, in Cuba.
Its cathedral episcopal see is St. Eugene's Cathedral, Ciego de Ávila.
As per 2015, it served 190,343 Catholics (40.9% of 465,628 total) on 7,887 km2 in 5 parishes and 36 missions with 8 priests (6 diocesan, 2 religious), 2 deacons, 18 lay religious (2 brothers, 16 sisters) and 1 seminarian .
(all Roman Rite)