Dinitrophenyl Explained

Dinitrophenyl should not be confused with dinitrophenol.

Dinitrophenyl is any chemical compound containing two nitro functional groups attached to a phenyl ring. It is a hapten used in vaccine preparation.[1] [2] Dinitrophenyl does not elicit any immune response on its own and it does not bind to any antigen.[3]

Notes and References

  1. 7923243. 1994. Berd. D. Activation markers on T cells infiltrating melanoma metastases after therapy with dinitrophenyl-conjugated vaccine. Cancer Immunology, Immunotherapy. 39. 3. 141–7. Maguire Jr. H. C.. Mastrangelo. M. J.. Murphy. G. 10.1007/s002620050105.
  2. 12218163. 2002. Manne. J. TCR rearrangement in lymphocytes infiltrating melanoma metastases after administration of autologous dinitrophenyl-modified vaccine. Journal of Immunology. 169. 6. 3407–12. Mastrangelo. M. J.. Sato. T. Berd. D. 10.4049/jimmunol.169.6.3407. free.
  3. Web site: Dinitrophenyl . NCI Drug Dictionary . National Cancer Institute.

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