| Dimitrios Sisinis | |
| Native Name: | Δημήτριος Σισίνης |
| Birth Date: | c. 1861 |
| Birth Place: | Gastouni, Kingdom of Greece |
| Allegiance: |  Kingdom of Greece |
| Serviceyears: | 1884-1917 1920-1921 |
| Rank: | Major General |
| Battles: | Greco-Turkish War (1897) Balkan Wars |
| Alma Mater: | Hellenic Military Academy |
| Relations: | Chrysanthos Sisinis (Brother) |
Dimitrios Sisinis (Greek, Modern (1453-);: Δημήτριος Σισίνης) was a Hellenic Army general.
Born in Gastouni in about 1861, he studied at the Hellenic Army Academy, graduating in 1884 as an Artillery Second Lieutenant. He fought in the Greco-Turkish War of 1897, and the Balkan Wars of 1912–13. In 1917 he was dismissed from the Army as a royalist during the National Schism, being re-instated in 1920 with the anti-Venizelist electoral victory. He finally retired from service on 12 October 1921 (O.S.) with the rank of Major General.