| Dimitrios Afentoulidis | |
| Height: | 1.76 m |
| Birth Date: | 1974 7, df=yes |
| Birth Place: | Kastoria, Greece |
| Position: | Midfielder |
| Years1: | 1994–1997 |
| Clubs1: | Kastoria |
| Years2: | 1997–2000 |
| Clubs2: | Ionikos |
| Years3: | 2001–2002? |
| Clubs3: | Chalkidona |
| Years4: | 2002–2003? |
| Clubs4: | Marko |
| Years5: | 2003–? |
| Clubs5: | Vyzas |
Dimitrios Afentoulidis (Greek, Modern (1453-);: Δημήτριος Αφεντουλίδης; born 21 July 1974) is a Greek former professional footballer who played as a midfielder. His father is Anestis Afentoulidis.