Dimethylglycine N-methyltransferase explained

Dimethylglycine N-methyltransferase
Ec Number:	2.1.1.161

Dimethylglycine N-methyltransferase (BsmB, DMT) is an enzyme with systematic name S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase (betaine-forming).^[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons S-adenosyl-L-homocysteine + betaine

This enzyme is purified from the marine cyanobacterium Synechococcus sp. WH8102.

Notes and References

1. Lu WD, Chi ZM, Su CD . Identification of glycine betaine as compatible solute in Synechococcus sp. WH8102 and characterization of its N-methyltransferase genes involved in betaine synthesis . Archives of Microbiology . 186 . 6 . 495–506 . December 2006 . 17019606 . 10.1007/s00203-006-0167-8 . 25210214 .