Dimemebfe Explained

Dimemebfe (5-MeO-BFE) is a recreational drug^[1] and research chemical. It acts as an agonist for the 5-HT_1A and 5-HT₂ family of serotonin receptors. It is related in structure to the psychedelic tryptamine derivative 5-MeO-DMT, but with the indole nitrogen replaced by oxygen, making dimemebfe a benzofuran derivative. It is several times less potent as a serotonin agonist than 5-MeO-DMT and with relatively more activity at 5-HT_1A, but still shows strongest effects at the 5-HT₂ family of receptors.^[2]

Legal status

Dimemebfe is a Schedule I controlled substance in the US state of Alabama.^[3]

See also

• 5-MeO-DiBF

Notes and References

1. The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog . Casale JF, Hays PA . Microgram Journal . 9 . 1 . 39–45 . 2015-02-23 . 2017-05-13 . https://web.archive.org/web/20170513130345/https://www.dea.gov/pr/microgram-journals/2012/mj9-1_39-45.pdf . dead .
2. Tomaszewski Z, Johnson MP, Huang X, Nichols DE . Benzofuran bioisosteres of hallucinogenic tryptamines . Journal of Medicinal Chemistry . 35 . 11 . 2061–4 . May 1992 . 1534585 . 10.1021/jm00089a017 .
3. Web site: Alabama Senate Bill 333 - Controlled substances, Schedule I, additional synthetic controlled substances and analogue substances included in, trafficking in controlled substance analogues, requisite weight increased, Secs. 13A-12-231, 20-2-23 am'd. . March 2014 . 28 September 2015.