Dillapiole Explained

Dillapiole is an organic chemical compound and essential oil commonly extracted from dill weed, though it can be found in a variety of other plants such as fennel root.^[1] This compound is closely related to apiole, having a methoxy group positioned differently on the benzene ring.^{[2] [3]} Dillapiole works synergically with certain insecticides like pyrethrins similarly to piperonyl butoxide, which likely results from inhibition of the MFO enzyme of insects.^[4]

No carcinogenicity was detected with parsley apiol or dill apiol in mice.^[5]

See also

• Pseudodillapiole

See also

• Apiole
• Phenylpropene

Notes and References

1. Book: Azeez, Shamina. Chemistry of Spices. 2008. Biddles Ltd.. Calicut, Kerala, India. 9781845934057. 227–241 [230].
2. Santos . P. A. G. . Figueiredo . A. C. . Lourenço . P. M. L. . Barroso . J. G. . Pedro . L. G. . Oliveira . M. M. . Schripsema . J. . Deans . S. G. . Scheffer . J. J. C. . Hairy root cultures of Anethum graveolens (Dill): Establishment, growth, time-course study of their essential oil and its comparison with parent plant oils. Biotechnology Letters . 24 . 12 . 1031–1036. 2002 . 10.1023/A:1015653701265 . 10120732 .
3. 10.1038/2151494b0 . Shulgin . A. T. . Sargent . T. . Psychotrophic phenylisopropylamines derived from apiole and dillapiole . Nature . 215 . 5109 . 1494–1495 . 1967. 4861200. 1967Natur.215.1494S . 26334093 .
4. IN . 128,129 . patent . Improvements in or relating to methylenedioxyphenyl derivatives . 1970-08-21 . 1970-10-24 . Mankombu Sambasivan Swaminathan .
5. 10.1093/carcin/5.12.1623. 6499113. 32P-Post-labelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. II. Newborn male B6C3F1 mice. Carcinogenesis. 5. 12. 1623–1628. 1984. Phillips. David H.. Reddy. M. Vijayaraj. Randerath. Kurt.