Dihydrobenzophenanthridine oxidase explained

Dihydrobenzophenanthridine oxidase
Ec Number:	1.5.3.12
Cas Number:	114051-83-1
Go Code:	0047132

Dihydrobenzophenanthridine oxidase (DHBP oxidase) is an enzyme. In the IUBMB Enzyme Nomenclature, dihydrobenzophenanthridine oxidase is .

Dihydrobenzophenanthridine oxidase produces oxidized forms of benzophenanthridine alkaloids:

• In Sanguinaria canadensis (bloodroot), dihydrobenzophenanthridine oxidase produces sanguinarine from dihydrosanguinarine, and chelirubine from dihydrochelirubine.
• In Eschscholzia californica (California poppy), dihydrobenzophenanthridine oxidase produces macarpine from dihydromacarpine.

External links

• Chelirubine, Macarpine and Sanguinarine Biosynthesis
• Ignatov A, Clark WG, Cline SD, Psenak M, Krueger J, Coscia CJ . Elicitation of dihydrobenzophenanthridine oxidase in Sanguinaria canadensis cell cultures . . 43 . 6 . 1141–4 . 1996 . 8987906 . 10.1016/S0031-9422(96)00540-7.
• Park SU, Yu M, Facchini PJ . Antisense RNA-mediated suppression of benzophenanthridine alkaloid biosynthesis in transgenic cell cultures of California poppy . Plant Physiol. . 128 . 2 . 696–706 . 2002 . 11842172 . 10.1104/pp.010741 . 148930.
• Rho D, Chauret N, Laberge N, Archambault J . Growth characteristics of Sanguinaria canadensis L. cell suspensions and immobilized cultures for production of benzophenanthridine alkaloids . Appl. Microbiol. Biotechnol. . 36 . 5 . 611–7 . 1992 . 1368065 . 10.1007/BF00183237.
• KEGG (Kyoto Encyclopedia of Genes and Genomes) Alkaloid biosynthesis I - Reference pathway