Didemnum fragile explained

Didemnum fragile is a species of sea squirt in the family Didemnidae.

Research

Didemnum fragile is of medical interest as it contains shishijimicin molecules, which have been seen to have potent anti-tumor activity in HeLa cells at picomolar concentrations.[1] Shishijimicin A was recently synthesized.[2]

Notes and References

  1. Oku. N. Matsunaga. S. Fusetani. N. Shishijimicins A-C, novel enediyne antitumor antibiotics from the ascidian Didemnum proliferum(1).. Journal of the American Chemical Society. 26 February 2003. 125. 8. 2044–5. 12590521. 10.1021/ja0296780.
  2. Web site: Rice lab synthesizes cancer-killing compound. 2015-07-13.