Diapolycopene oxygenase explained

Diapolycopene oxygenase
Ec Number:1.14.99.44

Diapolycopene oxygenase (crtP) is an enzyme with systematic name 4,4'-diapolycopene,AH2:oxygen oxidoreductase (4,4'-hydroxylating).[1] [2] This enzyme catalyses the following chemical reaction

4,4'-diapolycopene + 4 AH2 + 4 O2

\rightleftharpoons

4,4'-diapolycopenedial + 4 A + 6 H2O

Diapolycopene oxygenase is involved in the biosynthesis of C30 carotenoids such as staphyloxanthin.

Notes and References

  1. Mijts BN, Lee PC, Schmidt-Dannert C . Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution . Chemistry & Biology . 12 . 4 . 453–60 . April 2005 . 15850982 . 10.1016/j.chembiol.2005.02.010 . free .
  2. Tao L, Schenzle A, Odom JM, Cheng Q . Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde . Applied and Environmental Microbiology . 71 . 6 . 3294–301 . June 2005 . 15933032 . 1151855 . 10.1128/AEM.71.6.3294-3301.2005 .