Dianethole Explained

Dianethole is a naturally occurring organic compound that is found in anise and fennel.[1] [2] It is a dimeric polymer of anethole.[3] [4] It has estrogenic activity, and along with anethole and photoanethole, may be responsible for the estrogenic effects of anise and fennel.[5] [6] [7] [8] These compounds bear resemblance to the estrogens stilbene and diethylstilbestrol, which may explain their estrogenic activity.[9] In fact, it is said that diethylstilbestrol and related drugs were originally modeled after dianethole and photoanethole.[10]

See also

Notes and References

  1. Albert-Puleo. Michael. Fennel and anise as estrogenic agents. Journal of Ethnopharmacology. 2. 4. 1980. 337–344. 0378-8741. 10.1016/S0378-8741(80)81015-4. 6999244.
  2. Book: James A. Duke. Handbook of Phytochemical Constituents of GRAS Herbs and Other Economic Plants: Herbal Reference Library. 10 November 2000. CRC Press. 978-0-8493-3865-6. 257, 458.
  3. Book: K. V. Peter. Handbook of Herbs and Spices. 21 September 2012. Elsevier Science. 978-0-85709-568-8. 142–.
  4. Book: Finn Sandberg. Desmond Corrigan. Natural Remedies: Their Origins and Uses. 4 October 2001. CRC Press. 978-0-415-27202-5. 124–.
  5. Book: Steven Foster. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 12 November 2012. Routledge. 978-1-136-74501-0. 157–.
  6. Book: Thomas DeBaggio. Arthur O. Tucker. The Encyclopedia of Herbs: A Comprehensive Reference to Herbs of Flavor and Fragrance. 1 September 2009. Timber Press. 978-1-60469-134-4. 240–.
  7. Book: Ikhlas A. Khan. Ehab A. Abourashed. Leung's Encyclopedia of Common Natural Ingredients: Used in Food, Drugs and Cosmetics. 21 September 2011. John Wiley & Sons. 978-1-118-21306-3. 3–.
  8. Book: T. K. Lim. Edible Medicinal And Non-Medicinal Plants: Volume 5, Fruits. 2 February 2013. Springer Science & Business Media. 978-94-007-5653-3. 50–.
  9. Book: Kerry Bone. Simon Y. Mills. Principles and Practice of Phytotherapy,Modern Herbal Medicine,2: Principles and Practice of Phytotherapy. 2013. Elsevier Health Sciences. 978-0-443-06992-5. 559–.
  10. Jordan. V. C.. A Century of Deciphering the Control Mechanisms of Sex Steroid Action in Breast and Prostate Cancer: The Origins of Targeted Therapy and Chemoprevention. Cancer Research. 69. 4. 2009. 1243–1254. 0008-5472. 10.1158/0008-5472.CAN-09-0029. 19208829.

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