Diaminobutyrate decarboxylase explained

Diaminobutyrate decarboxylase
Ec Number:	4.1.1.86

The enzyme diaminobutyrate decarboxylase catalyzes the chemical reaction

L-2,4-diaminobutanoate

\rightleftharpoons propane-1,3-diamine + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming). Other names in common use include DABA DC, L-2,4-diaminobutyrate decarboxylase, and L-2,4-diaminobutanoate carboxy-lyase.

References

• Yamamoto S, Tsuzaki Y, Tougou K, Shinoda S . 1992 . Purification and characterization of L-2,4-diaminobutyrate decarboxylase from Acinetobacter calcoaceticus . J. Gen. Microbiol. . 138 . 1461 - 5 . 1512577 . 7 . 10.1099/00221287-138-7-1461. free .
• Ikai H, Yamamoto S . 1994 . Cloning and expression in Escherichia coli of the gene encoding a novel L-2,4-diaminobutyrate decarboxylase of Acinetobacter baumannii . FEMS Microbiol. Lett. . 124 . 225 - 8 . 7813892 . 2 . 10.1111/j.1574-6968.1994.tb07288.x. free .
• Ikai H, Yamamoto S . 1997 . Identification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii . J. Bacteriol. . 179 . 5118 - 25 . 9260954 . 16 . 179370 . 10.1128/jb.179.16.5118-5125.1997.