Diacetyl monoxime explained

Diacetyl monoxime is a chemical compound described by the formula CH3C(O)C(NOH)CH3. This colourless solid is the monooxime derivative of the diketone butane-2,3-dione (also known as diacetyl and biacetyl). Its biological effects include inhibiting certain ATPases.[1]

Preparation

The compound can be prepared from butanone by reaction with ethyl nitrite. It is an intermediate in the preparation of dimethylglyoxime:

Uses

Diacetyl monoxime can be used with thiosemicarbazide to selectively detect small amounts of urea in the presence of other nitrogen-containing compounds.[2]

Notes and References

  1. Does 2,3-butanedione monoxime inhibit nonmuscle myosin?. Forer, Arthur . Fabian, Lacramioara . Protoplasma. 2005. 225. 1–2 . 1–4. 10.1007/s00709-004-0077-z. 15868207 . 10475777 .
  2. Douglas . L. A. . Bremner . J. M. . 1970-02-01 . Colorimetric Determination of Microgram Quantities of Urea . Analytical Letters . 3 . 2 . 79–87 . 10.1080/00032717008067782 . 0003-2719.

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