| Dhaleshwari River | |
| Map: | BD Map Central Bangladesh.jpg |
| Subdivision Type1: | Country |
| Subdivision Name1: | Bangladesh |
| Length: | 160km (100miles) |
| Discharge1 Location: | Shitalakshya River |
| Source1: | Jamuna River |
The Dhaleshwari River (Bengali: ধলেশ্বরী|Dhalēśbarī, Dhôleshshori) is a distributary, 160km (100miles) long, of the Jamuna River in central Bangladesh. It branches off the Jamuna near the northwestern tip of Tangail District. After that it divides into two branches: the north branch retains the name Dhaleshwari and merges with the other branch, the Kaliganga River at the southern part of Manikganj District. Finally the merged flow meets the Shitalakshya River near Narayanganj District. This combined flow goes southwards to merge into the Meghna River.
Average depth of river is 122feet and maximum depth is 265feet.
Pollution of the Dhaleshwari River by the textile industry has been described by academics as an ecocide.