Dextrothyroxine Explained

Dextrothyroxine (trade name Choloxin) is a dextrorotary isomer of thyroxine.[1] It saw research as a cholesterol-lowering drug[2] but was pulled due to cardiac side-effects. It increases hepatic lipase which in turn improves utilization of triglycerides and decreases levels of lipoprotein(a) in blood serum.[3]

See also

Notes and References

  1. Web site: Dextrothyroxine (Code C61719) . 2011-11-14 . NCI Thesaurus . National Cancer Institute . 2020-01-28.
  2. Bantle JP, Hunninghake DB, Frantz ID, Kuba K, Mariash CN, Oppenheimer JH . Comparison of effectiveness of thyrotropin-suppressive doses of D- and L-thyroxine in treatment of hypercholesterolemia . The American Journal of Medicine . 77 . 3 . 475–81 . September 1984 . 6475988 . 10.1016/0002-9343(84)90107-4 .
  3. Bommer C, Werle E, Walter-Sack I, Keller C, Gehlen F, Wanner C, Nauck M, März W, Wieland H, Bommer J . 6 . D-thyroxine reduces lipoprotein(a) serum concentration in dialysis patients . Journal of the American Society of Nephrology . 9 . 1 . 90–6 . January 1998 . 10.1681/ASN.V9190 . 9440092 .

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