Dexetimide Explained

Dexetimide (brand name Tremblex) is a piperidine anticholinergic. It is a muscarinic antagonist that is used to treat drug induced parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.[1] [2]

Notes and References

  1. Dom R, Van Lommel R, Baro F . A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent . Acta Psychiatrica Scandinavica . 47 . 4 . 399–410 . 1971 . 4947805 . 10.1111/j.1600-0447.1971.tb03697.x . 10591790 .
  2. Huygens H, Vereecken JL, Tanghe A . Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action . Psychiatria, Neurologia, Neurochirurgia . 76 . 4 . 251–9 . 1973 . 4581374 .

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