Metizolam Explained

Metizolam (also known as desmethyletizolam) is a thienotriazolodiazepine that is the demethylated analogue of the closely related etizolam.^{[1] [2] [3] [4] [5] [6]}

Legal status

Following its sale as a designer drug,^[7] metizolam was classified as controlled substance in Sweden on 26. January 2016.^[8]

See also

• List of benzodiazepine designer drugs

Notes and References

1. Weber K, Bauer A, Langbein A, Daniel H . Heteroaromaten mit anellierten Siebenringen, III. Umwandlung von Thienotriazolooxazepinen in Diazepine. Justus Liebigs Annalen der Chemie. 20 September 1978 . 1099-0690 . 1257–1265 . 1978 . 8 . 10.1002/jlac.197819780806 . de .
2. US . 3904641 . Triazolothienodiazepine compounds . Nakanishi M, Tahara T, Araki K, Shiroki M . Welfide Corp . 9 September 1975.
3. EP . 0776892 . Thienylazole compound and thienotriazolodiazepine compound . Hiroshi K, Ehara Syuji E, Hideaki S, Moriwaki Minoru M, Kenichi O . Yoshitomi Pharmaceutical Industries, Ltd. . 1997-06-04.
4. EP . 0315698 . Thieno(triazolo)diazepine compounds and medicinal application of the same . Yoshitomi Pharmaceutical Industries, Ltd. . 1993-03-03 . Moriwaki M, Abe M, Mikashima H, Tahara T .
5. Moosmann B, Bisel P, Franz F, Huppertz LM, Auwärter V . Characterization and in vitro phase I microsomal metabolism of designer benzodiazepines - an update comprising adinazolam, cloniprazepam, fonazepam, 3-hydroxyphenazepam, metizolam and nitrazolam . Journal of Mass Spectrometry . 51 . 11 . 1080–1089 . November 2016 . 27535017 . 10.1002/jms.3840 . 2016JMSp...51.1080M .
6. Kintz P, Richeval C, Jamey C, Ameline A, Allorge D, Gaulier JM, Raul JS . Detection of the designer benzodiazepine metizolam in urine and preliminary data on its metabolism . Drug Testing and Analysis . 9 . 7 . 1026–1033 . July 2017 . 27671107 . 10.1002/dta.2099 .
7. Web site: Desmethyletizolam . New Synthetic Drugs Database . 2016-01-16 . https://web.archive.org/web/20160625053740/http://nsddb.eu/substance/573/ . 2016-06-25 . dead .
8. Web site: 31 nya ämnen kan klassas som narkotika eller hälsofarlig vara . Folkhälsomyndigheten . sv . November 2015.