| Derek Chamberlain | |
| Fullname: | Derek Colin Chamberlain |
| Birth Date: | 6 January 1933 |
| Birth Place: | Nottingham, England |
| Years1: | 1952–1953 |
| Clubs1: | Parliament Street Methodists |
| Years2: | 1953–1954 |
| Caps2: | 0 |
| Goals2: | 0 |
| Years3: | 1956–1958 |
| Caps3: | 43 |
| Goals3: | 0 |
| Years4: | 1958–1959 |
| Clubs4: | York City |
| Caps4: | 0 |
| Goals4: | 0 |
| Totalcaps: | 43 |
| Totalgoals: | 0 |
Derek Colin Chamberlain (6 January 1933 – 2013) was an English professional footballer who played in the Football League for Mansfield Town.