| Position: | Goaltender |
| Catches: | Left |
| Height Ft: | 6 |
| Height In: | 4 |
| Weight Lb: | 209 |
| Played For: | HC CSKA Moscow Metallurg Magnitogorsk HC Spartak Moscow Khimik Moscow Oblast |
| Ntl Team: | RUS |
| Birth Date: | January 27, 1978 |
| Birth Place: | Moscow, USSR |
| Draft: | 209th overall |
| Draft Year: | 1996 |
| Draft Team: | Florida Panthers |
| Career Start: | 1996 |
| Career End: | 2004 |
Denis Khlopotnov (born January 27, 1978) is a Russian former professional ice hockey goaltender. He played in the Russian Superleague for HC CSKA Moscow, Metallurg Magnitogorsk, HC Spartak Moscow and Khimik Moscow Oblast. He was drafted 209th overall by the Florida Panthers in the 1996 NHL Entry Draft.