Delta6-protoilludene synthase explained

Δ^6-protoilludene synthase
Ec Number:	4.2.3.135

Δ⁶-Protoilludene synthase (EC 4.2.3.135, 6-protoilludene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, Δ⁶-protoilludene-forming).^[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate

\rightleftharpoons Δ⁶-protoilludene + diphosphate

This enzyme is isolated from the fungus Armillaria gallica.

Notes and References

1. Cloning and characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides . Engels B, Heinig U, Grothe T, Stadler M, Jennewein S . J. Biol. Chem. . 2011 . 286 . 9 . 6871–6878 . 21148562 . 10.1074/jbc.m110.165845 . 3044942. free .