Delphinidin 3',5'-O-glucosyltransferase explained

Delphinidin 3',5'-O-glucosyltransferase
Ec Number:	2.4.1.249

Delphinidin 3',5'-O-glucosyltransferase (UDP-glucose:anthocyanin 3',5'-O-glucosyltransferase, UA3'5'GZ) is an enzyme with systematic name UDP-glucose:delphinidin 3-O-(6-O-malonyl)-beta-D-glucoside 3'-O-glucosyltransferase.^[1] This enzyme catalyses the following chemical reaction

2 UDP-glucose + delphinidin 3-O-(6-O-malonyl)-beta-D-glucoside

\rightleftharpoons 2 UDP + delphinidin 3-O-(6-O-malonyl)-beta-D-glucoside-3',5'-di-O-beta-D-glucoside (overall reaction)

(1a) UDP-glucose + delphinidin 3-O-(6-O-malonyl)-beta-D-glucoside

\rightleftharpoons UDP + delphinidin 3-O-(6-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside

(1b) UDP-glucose + delphinidin 3-O-(6-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside

\rightleftharpoons UDP + delphinidin 3-O-(6-O-malonyl)-beta-D-glucoside-3',5'-di-O-beta-D-glucoside

This enzyme catalyses two reactions in the biosynthesis of ternatin C5.

Notes and References

1. Kogawa K, Kato N, Kazuma K, Noda N, Suzuki M . Purification and characterization of UDP-glucose: anthocyanin 3',5'-O-glucosyltransferase from Clitoria ternatea . Planta . 226 . 6 . 1501–9 . November 2007 . 17668234 . 10.1007/s00425-007-0584-1 .