DelNS1-2019-nCoV-RBD-OPT explained

Type:vaccine
Target:SARS-CoV-2
Vaccine Type:viral
Tradename:Pneucolin
Routes Of Administration:Intranasal
Synonyms:DelNS1-nCoV-RBD LAIV[1]

DelNS1-2019-nCoV-RBD-OPT is a COVID-19 vaccine developed by Beijing Wantai Biological, Xiamen University and the University of Hong Kong.[2] [3] [4] It is administered as a single dose intranasal spray.[5]

On 14 December 2022, the vaccine was listed by the National Health Commission of China as a secondary booster dose option for people who have completed their third doses of inactivated COVID-19 vaccines for 6 months or longer.[6]

Notes and References

  1. A Study to Evaluate Safety and Immunogenicity of DelNS1-nCoV-RBD LAIV for COVID-19 . clinicaltrials.gov . 29 April 2021 . United States National Library of Medicine . 3 May 2021 .
  2. News: China's nasal-spray COVID-19 vaccines undergoing clinical trials: official . 10 July 2021 . Xinhua . 11 June 2021.
  3. Web site: A Phase I Clinical Trial of Influenza virus Vector COVID-19 Vaccine for intranasal Spray (DelNS1-2019-nCoV-RBD-OPT1) . chictr.org.cn . Chinese Clinical Trial Registry . 24 March 2021 . live. https://web.archive.org/web/20210407054232/https://clinicaltrials.gov/ct2/show/NCT04809389 . 7 April 2021 .
  4. Web site: A Phase II Clinical Trial of Influenza virus Vector COVID-19 Vaccine for intranasal Spray (DelNS1-2019-nCoV-RBD-OPT1) . chictr.org.cn . Chinese Clinical Trial Registry . 24 March 2021 . live. https://web.archive.org/web/20201114133923/http://www.chictr.org.cn/showprojen.aspx?proj=63754 . 14 November 2020 .
  5. Mi H, Chen Q, Lin H, He T, Zhang R, Ren S, Liu L, Wang J, Huang H, Wang M, Guo Z, Su C . Short-term effectiveness of single-dose intranasal spray COVID-19 vaccine against symptomatic SARS-CoV-2 Omicron infection in healthcare workers: a prospective cohort study . eClinicalMedicine . 67 . 102374 . January 2024 . 38169940 . 10758709 . 10.1016/j.eclinm.2023.102374 .
  6. Web site: 关于印发新冠病毒疫苗第二剂次加强免疫接种实施方案的通知 . Notice on the implementation plan for the second dose of new coronavirus vaccine booster vaccination . National Health Commission. 2022-12-14. zh. 2022-12-14.