Deacetylasperulosidic acid explained

Deacetylasperulosidic acid is an iridoid compound found in a few medicinal plants, such as Morinda citrifolia.[1] Some in vitro and in vivo bioactivities of deacetylasperulosidic acid include anti-inflammatory, analgesic, anti-cancer, antioxidant, anti-arthritic, anti-mutagenic, anti-clastogenic, and hepatoprotection.[2] [3] [4] [5] [6]

Notes and References

  1. 10.1021/jf071359a . Potterat O, Von Felten R, Dalsgaard PW, Hamburger M . Identification of TLC markers and quantification by HPLC-MS of various constituents in noni fruit powder and commercial noni-derived products . J. Agric. Food Chem. . 2007 . 55 . 18 . 7489–7494 . 17696360.
  2. Akihisa . T . Matsumoto . K . Tokuda . H . Yasukawa . K . Seino . K . Nakamoto . K . Kuninaga . H . Suzuki . T . Kimura . Y . Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni) . Journal of Natural Products . 70 . 5 . 754–7 . 2007 . 17480098 . 10.1021/np068065o .
  3. Liu . G . Bode . A . Ma . WY . Sang . S . Ho . CT . Dong . Z . Two novel glycosides from the fruits of Morinda citrifolia (noni) inhibit AP-1 transactivation and cell transformation in the mouse epidermal JB6 cell line. . Cancer Research . 61 . 15 . 5749–56 . 2001 . 11479211.
  4. 10.1248/bpb.26.352 . Ling . SK . Tanaka . T . Kouno . I . Effects of iridoids on lipoxygenase and hyaluronidase activities and their activation by beta-glucosidase in the presence of amino acids. . Biological & Pharmaceutical Bulletin . 26 . 3 . 352–6 . 2003 . 12612446. free .
  5. 10.1007/BF02972979 . Kim DH, Lee HJ, Oh YJ, Kim MJ, Kim SH, Jeong TS, Baek NI . Iridoid glycosides isolated from Oldenlandia diffusa inhibit LDL-oxidation . Arch Pharm Res . 2005 . 28 . 1156–1160 . 10. 16276972 . 11924214 .
  6. Nakamura . T . Nakazawa . Y . Onizuka . S . Satoh . S . Chiba . A . Sekihashi . K . Miura . A . Yasugahira . N . Sasaki . YF . Antimutagenicity of Tochu tea (an aqueous extract of Eucommia ulmoides leaves): 1. The clastogen-suppressing effects of Tochu tea in CHO cells and mice . Mutation Research . 388 . 1 . 7–20 . 1997 . 9025787 . 10.1016/s1383-5718(96)00096-4.

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