| De Soto Open Invitational | |
| Location: | Sarasota, Florida |
| Establishment: | 1960 |
| Course: | De Soto Lakes Golf & Country Club |
| Par: | 71 |
| Tour: | PGA Tour |
| Format: | Stroke play |
| Month Played: | March |
| Final Year: | 1960 |
| Aggregate: | 276 Sam Snead (1960) |
| To-Par: | −8 as above |
| Final Champion: |  Sam Snead |
| Map: | USA#USA Florida |
| Map Relief: | yes |
| Map Label: | De Soto Lakes G&CC |
| Coordinates: | 27.365°N -82.488°W |
The De Soto Open Invitational was a golf tournament on the PGA Tour that was held from March 24 - 27, 1960 at the De Soto Lakes Golf & Country Club[1] in Sarasota, Florida. The club is now known as Palm-Aire Country Club and is located at Whitfield Avenue and Country Club Way. The event was won by then 47-year-old Sam Snead.[2]