| Official Name: | De Soto, Nebraska |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Nebraska |
| Subdivision Type2: | County |
| Subdivision Name2: | Washington |
| Unit Pref: | Imperial |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 1007 |
| Coordinates: | 41.5012°N -96.0567°W |
| Postal Code Type: | ZIP code |
| Area Code: | 402 |
De Soto is an unincorporated community in Washington County, Nebraska, United States. It was named in honor of the sixteenth-century Spanish explorer, Hernando De Soto. De Soto was founded in 1855 and served as the county seat from 1858-1866. During its heyday, the town hosted many flourishing new businesses: hotels, saloons, stores, newspapers and banks.[1]
De Soto contains farmland with about three families residing there.[2]