David Taylor (professor) explained
David Taylor FFRPS FRPharmS (born 1963) is a British professor. He is the head of the Pharmaceutical Sciences Clinical Academic Group within King's Health Partners. Taylor has been lead author and editor of the Maudsley Prescribing Guidelines in Psychiatry since 1994. In 2014, Taylor was named as one of the top 100 clinical leaders in the UK National Health Service.[1]
Early life and education
Taylor was born in Leicester in 1963 and attended Loughborough Grammar School (1975-1982). He is the second of four brothers. His younger brother is the presenter and historian, Stephen Taylor.[2] His father, James Taylor CChem MRSC, contributed to the development of sodium cromoglycate.[3]
Taylor was guitarist in New Wave group The Thought Police, who supported Theatre of Hate on their 1981 UK tour.
A keen rugby player, Taylor played three seasons for Loughborough Grammar School first team and was later captain of Old Pauline FC 1st XV, for whom he made over 300 appearances, many alongside fellow Old Loughburian Patrick MacLarnon.
In 2023, Taylor completed the London Marathon in just over four hours.
Taylor obtained a BSc in pharmacy and an MSc in clinical pharmacy from the University of Brighton. He later gained a PhD in clinical pharmacology at King’s College, London. He is a fellow of the Royal Pharmaceutical Society of Great Britain (FRPharmS),[4] a fellow of that organisation’s faculty (FFRPS) and an elected fellow of the Royal College of Physicians, Edinburgh (FRCPEdin). In 2021 he was made an honorary fellow of the Royal College of Psychiatrists (FRCPsych Hon) in recognition of his "outstanding contribution to the profession and the cause of mental health".
Career
Taylor's first experience in psychiatry was in 1986 – a brief placement at the Towers Hospital in Leicester. He then worked in general medicine at hospitals in London and Sydney until joining the Maudsley hospital in 1993. In 1997 Taylor founded the national centre for information on drugs in psychiatry, part of the UKMi network. He has been head of pharmacy since 1995 and Director of Pharmacy and Pathology at the South London and Maudsley NHS Foundation Trust since 2000.
In 2008, Taylor was awarded a chair in psychopharmacology at King’s College, London and also made honorary professor at the Institute of Psychiatry. Since 2010, Taylor has been head of the Pharmaceutical Sciences Clinical Academic Group within King's Health Partners.[5]
Public works
Taylor was chairman of the UK Psychiatric Pharmacy Group (1997-1999) and the foundation president of the College of Mental Health Pharmacists, a role recognised by the award of a lifetime fellowship (FCMHP). He was a member of the government-appointed panel which brought in laws in drug driving[6] and is currently a member of the Advisory Council on the Misuse of Drugs.[7]
Taylor has been a member of several NICE panels responsible for drawing up treatment guidelines in mental health, including the 2022 guideline on depression in adults.[8]
Since 2011 he has been editor-in-chief of the journal Therapeutic Advances in Psychopharmacology[9] which was launched in the same year. The journal has an official Impact Factor of 3.4[10] and is ranked 79th out of 276 psychiatry journals.
Taylor is widely recognised as an expert witness on the effect of drugs on behaviour and has given testimony on over two hundred civil and criminal cases.
Research
Taylor has authored around 400 papers (H index 76) in journals such as the Lancet, BMJ, British Journal of Psychiatry and Journal of Clinical Psychiatry, on subjects ranging from the value of long-acting antipsychotic injections,[11] [12] the efficacy of psilocybin as an antidepressant and the efficacy and safety of agomelatine. Taylor’s research has helped further understanding of the use of clozapine.[13] [14] [15] [16] [17] In 2022 he suggested a refined phenotype for genetic studies into clozapine-related agranulocytosis.[18] He has also developed a genetic test predicting response to clozapine and the risk of agranulocytosis. This test is marketed in the UK by Psychiatric Genetics Ltd. Most recently Taylor has tackled the controversial subjects of discontinuation of antidepressants[19] [20] and antipsychotics.[21] [22] He is co-founder of 428 Pharma a company developing the world's first antidepressant long-acting injection which is designed for use both as longterm treatment and, at different dosage levels, as a means of successfully withdrawing from antidepressant treatment. Taylor has pioneered the use of point-of-care capillary testing for clozapine[23] [24]
Maudsley Prescribing Guidelines
Taylor was the originator of the idea of an evidenced-based mental health prescribing guideline along with the late professor Robert Kerwin and has made a major and unique contribution by writing the Maudsley Prescribing Guidelines[25] for over 25 years. Taylor is the de facto editor of this publication and is the only author to be credited on all 14 editions. The Maudsley Prescribing Guidelines[26] [27] [28] have sold over 300,000 copies in thirteen languages. The 14th edition was published in June 2021. He has also co-written four other books in the Maudsley Prescribing Guidelines series, including The Maudsley Deprescribing Guidelines, first published in January 2024.
Lectures
Professor Taylor has lectured throughout the world, including tours of New Zealand (2011), Hong Kong (2016), Australia (2019) and Japan (2019).He was a keynote speaker at the 2018 annual meeting of Royal Australian and New Zealand College of Psychiatrists in Auckland, at the Royal College of Psychiatrists annual meeting in London in 2019,[29] and at The 119th Annual Meeting of the Japanese Society of Psychiatry and Neurology in 2023.
Selected publications
- The Use of Drugs in Psychiatry, Cookson J, Taylor D, Katona C, 2002. Gaskell.
- Schizophrenia in Focus. 2006. David M Taylor. Pharmaceutical Press
- Atypical antipsychotics and weightgain—a systematic review, DM Taylor, R McAskill, Acta Psychiatrica Scandinavica 101 (6), 416–432, 2000
- Antidepressant efficacy of agomelatine: meta-analysis of published and unpublished studies. BMJ 2014 Mar 19;348:g1888. David Taylor, Anna Sparshatt, Seema Varma, Olubanke Olofinjana
- Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study, RL Carhart-Harris, M Bolstridge, J Rucker, CMJ Day, D Erritzoe, M Kaelen, The Lancet Psychiatry 3 (7), 619-627 2016.
- Tapering of SSRI treatment to mitigate withdrawal symptoms. Lancet Psychiatry. 2019; 6: 538–546. Horowitz MA Taylor D
- The Maudsley Guidelines for Physical Health Conditions in Psychiatry. 2020. David Taylor, Fiona Gaughran, Toby Pillinger. Wiley Blackwell.
- Covid has led to record levels of antidepressant use – but withdrawal can be difficult - David Taylor
External links
Notes and References
- Web site: Trivedi . Shreshtha . Clinical leaders 2014 . Health Service Journal . en.
- Web site: 2018-01-18 . TV & Media . 2023-01-31 . Stephen Taylor, WW2 Relic Hunter . en.
- A moisture transfer effect in hard gelatin capsules of sodium cromoglycate. 4150598. 1973. Bell. J. H.. Stevenson. N. A.. Taylor. J. E.. The Journal of Pharmacy and Pharmacology. 25. Suppl:96P–103.
- Web site: Society appoints 24 new Fellows . Royal Pharmaceutical Society of Great Britain. London . 11 December 2009. 3 June 2021.
- Web site: Professor David Taylor MSc PhD FFRPS FRPharmS . King's People. King's College London. 3 June 2021.
- Expert Panel of Drug Driving. DRIVING UNDER THE INFLUENCE OF DRUGS. March 2013. Department for Transport (DfT).
- Web site: Advisory Council on the Misuse of Drugs Membership . GOV.UK. 3 June 2021. en.
- https://www.nice.org.uk/guidance/ng222/documents/committee-member-list-2
- Web site: Therapeutic Advances in Psychopharmacology Editorial Team. SAGE Journals. 3 June 2021. en.
- Web site: 29 June 2024 . Journal Indexing and Metrics: Therapeutic Advances in Psychopharmacology . 2024-07-29 . journals.sagepub.com.
- Taylor. D. M.. Sparshatt. A.. O’Hagan. M.. Dzahini. O.. September 2016. Effect of paliperidone palmitate on hospitalisation in a naturalistic cohort – a four-year mirror image study. European Psychiatry. en. 37. 43–48. 10.1016/j.eurpsy.2016.04.009. 27447102. 13769572. 0924-9338.
- Taylor. D.. Fischetti. C.. Sparshatt. A.. Thomas. A.. Bishara. D.. Cornelius. V.. 2009. Risperidone long-acting injection: a 6-year mirror-image study of healthcare resource use. Acta Psychiatrica Scandinavica. en. 120. 2. 97–101. 10.1111/j.1600-0447.2009.01352.x. 19207128. 39369119. 1600-0447.
- Bachmann. C. J.. Aagaard. L.. Bernardo. M.. Brandt. L.. Cartabia. M.. Clavenna. A.. Fusté. A. Coma. Furu. K.. Garuoliené. K.. Hoffmann. F.. Hollingworth. S.. 2017. International trends in clozapine use: a study in 17 countries. Acta Psychiatrica Scandinavica. en. 136. 1. 37–51. 10.1111/acps.12742. 28502099. 206969000. 1600-0447.
- Taylor. David. August 1997. Pharmacokinetic interactions involving clozapine. The British Journal of Psychiatry. en. 171. 2. 109–112. 10.1192/bjp.171.2.109. 9337943. 5033129. 0007-1250.
- Oloyede. Ebenezer. Casetta. Cecilia. Dzahini. Olubanke. Segev. Aviv. Gaughran. Fiona. Shergill. Sukhi. Mijovic. Alek. Helthuis. Marinka. Whiskey. Eromona. MacCabe. James Hunter. Taylor. David. There Is Life After the UK Clozapine Central Non-Rechallenge Database. Schizophrenia Bulletin. 2021. 47. 4. 1088–1098. en. 10.1093/schbul/sbab006. 33543755. 8266568.
- Whiskey. Eromona. Barnard. Alex. Oloyede. Ebenezer. Dzahini. Olubanke. Taylor. David M.. Shergill. Sukhwinder S.. An evaluation of the variation and underuse of clozapine in the United Kingdom. Acta Psychiatrica Scandinavica. 2021. 143. 4. 339–347. en. 10.1111/acps.13280. 33501659. 1600-0447. free.
- Taylor. David. Atkins. Matthew. Harland. Robert. Baburina. Irina. MacCabe. James H.. Salamone. Salvatore J.. McGuire. Philip. March 2021. Point-of-care measurement of clozapine concentration using a finger-stick blood sample. Journal of Psychopharmacology. 35. 3. 279–283. 10.1177/0269881121991567. 1461-7285. 33579175. 231911366.
- Taylor . David . Vallianatou . Kalliopi . Whiskey . Eromona . Dzahini . Olubanke . MacCabe . James . 2022-03-14 . Distinctive pattern of neutrophil count change in clozapine-associated, life-threatening agranulocytosis . Schizophrenia . en . 8 . 1 . 21 . 10.1038/s41537-022-00232-0. 35288577 . 8920060 . 2334-265X.
- Horowitz. Mark Abie. Taylor. David. June 2019. Tapering of SSRI treatment to mitigate withdrawal symptoms. The Lancet Psychiatry. 6. 6. 538–546. 10.1016/s2215-0366(19)30032-x. 30850328. 73507008. 2215-0366.
- Horowitz . Mark Abie . Taylor . David . 2022-04-27 . Distinguishing relapse from antidepressant withdrawal: clinical practice and antidepressant discontinuation studies . BJPsych Advances . 28 . 5 . en . 297–311 . 10.1192/bja.2021.62 . 251885585 . 2056-4678. free .
- Horowitz. Mark Abie. Murray. Robin M.. Taylor. David. 2020-08-05. Tapering Antipsychotic Treatment. JAMA Psychiatry. 78. 2. 125–126. en. 10.1001/jamapsychiatry.2020.2166. 32777027. 225366466.
- Horowitz. Mark Abie. Jauhar. Sameer. Natesan. Sridhar. Murray. Robin M. Taylor. David. 2021-03-23. A Method for Tapering Antipsychotic Treatment That May Minimize the Risk of Relapse. Schizophrenia Bulletin. 47. sbab017. 1116–1129. 10.1093/schbul/sbab017. 33754644. 8266572. 0586-7614. free.
- Atkins . Matthew . McGuire . Philip . Balgobin . Bhirundra . Desouza . Neville . Taylor . David . January 2023 . Haematological point of care testing for clozapine monitoring . Journal of Psychiatric Research . en . 157 . 66–71 . 10.1016/j.jpsychires.2022.11.027.
- Taylor . David . Atkins . Matthew . Harland . Robert . Baburina . Irina . MacCabe . James H . Salamone . Salvatore J . McGuire . Philip . March 2021 . Point-of-care measurement of clozapine concentration using a finger-stick blood sample . Journal of Psychopharmacology . en . 35 . 3 . 279–283 . 10.1177/0269881121991567 . 0269-8811.
- The Maudsley Prescribing Guidelines in Psychiatry, 12th ed. 10.4088/JCP.16bk10716. 2016. Jenkins. James A.. Kontos. Nicholas. The Journal of Clinical Psychiatry. 77. 4. e469. free.
- Feetam. Celia. 2006. The Maudsley 2005–2006 Prescribing Guidelines (8th edn). David Taylor, Robert Kerwin & Carol Paton. London: Taylor & Francis, 2005, £19.95 pb, pp. 383. ISBN 1841845000. Psychiatric Bulletin. en. 30. 11. 437. 10.1192/pb.30.11.437-a. 0955-6036. free.
- The Maudsley: prescribing guidelines (book review). Pharmaceutical Journal. en.
- Jenkins. James. 2016. The Maudsley Prescribing Guidelines in psychiatry 12th Ed. Journal of Clinical Psychiatry. 77. 4. e469. 10.4088/JCP.16bk10716. free.
- Web site: International Congress of the Royal College of Psychiatrists Programme 1st July- 4th July 2019. 3 June 2021.