| Office: | Member of Parliament for South Northamptonshire |
| Termstart: | 4 July 1892 |
| Termend: | 13 July 1895 |
| Party: | Liberal |
| Birth Date: | 1861 |
| Death Date: | 12 January 1918 |
| Predecessor: | Rainald Knightley |
| Successor: | Edward Douglas-Pennant |
David Charles Guthrie (1861 – 12 January 1918) was a British Liberal Party politician who served as Member of Parliament for South Northamptonshire in the 25th Parliament between 1892 and 1895.[1]
Guthrie was first elected at the 1892 general election.