| David C. Henderson | |
| Birth Place: | Bedford, Ohio, U.S. |
| Player Years1: | 1938 |
| Player Team1: | Wooster |
| Player Positions: | Quarterback |
| Coach Sport1: | Football |
| Coach Years2: | 1946–1951 |
| Coach Team2: | Kenyon |
| Coach Years3: | 1952–1953 |
| Coach Team3: | Allegheny |
| Coach Sport4: | Basketball |
| Coach Years5: | 1948–1952 |
| Coach Team5: | Kenyon |
| Overall Record: | 15–40–2 (football) 24–40 (basketball) |
David C. Henderson (born) was an American football player and coach of football and basketball. He served as the head football coach at Kenyon College from 1946 to 1951 and at Allegheny College from 1952 to 1953, compiling a career college football record of 15–40–2 Henderson was also the head basketball coach at Kenyon for four seasons, from 1948 to 1952, tallying a mark of 24–40. He played football at the College of Wooster, from which he graduated in 1939.[1]