David Ballou Explained
| David P. Ballou |
| Citizenship: | American |
| Nationality: | American |
| Fields: | Biochemistry |
| Workplaces: | University of Michigan |
| Alma Mater: | Antioch College
University of Michigan |
| Thesis Year: | 1971 |
| Doctoral Advisor: | Graham Palmer |
| Academic Advisors: | Vince Massey
Minor J. Coon |
| Known For: | Presteady-state enzyme kinetics methods |
| Spouse: | Jean Ballou[1] |
David P. Ballou is a professor emeritus of biological chemistry at the University of Michigan Medical School in the United States.[1] He is best known for his development of rapid-reaction techniques,[2] including stopped flow and rapid freeze-quench EPR methods,[3] as tools to study the mechanisms of enzymes containing flavin,[4] iron,[5] cobalamin, or pyridoxal phosphate cofactors. Many of these studies were performed in collaboration with other scientists, most often with colleagues at Michigan.[6]
Biography
David Ballou grew up in Connecticut.[2] He received a B.S. in chemistry from Antioch College in 1965. In 1971, he received a Ph.D. from the University of Michigan under the supervision of Graham Palmer. From 1971-1972, he was a postdoctoral fellow with Vincent Massey and Minor J. Coon at the University of Michigan. He has been a faculty member in the Department of Biological Chemistry at the University of Michigan Medical School since 1972.In 2007, Ballou became a Fellow of the American Association for the Advancement of Science in recognition of his discovery of enzyme intermediates that are involved in biological oxidation reactions.[7] His most cited paper, l, "Oxidative Protein Folding Is Driven by the Electron Transport System",[8] has been cited 311 times according to Google Scholar, and he has contributed to 25 papers having more than 0100 citations each.[9]
Books
- Fundamental Laboratory Approaches for Biochemistry and Biotechnology (2nd Ed) (2009) by Alexander J. Ninfa, David P. Ballou, and Marilee Benore. Published by Wiley .
External links
Notes and References
- Web site: David Ballou, Ph.D. . 12 August 2014 . 2020-01-20 . https://web.archive.org/web/20170703183702/https://medicine.umich.edu/dept/biochem/david-ballou-phd . 2017-07-03 . live .
- Cheng Z, Zhang J, Ballou DP, ((Williams CH Jr)) . Reactivity of Thioredoxin as a Protein Thiol-Disulfide Oxidoreductase . Chemical Reviews . 111 . 9 . 5768–5783 . 2011 . 21793530 . 10.1021/cr100006x . 3212873 .
- Ballou DP, Palmer GA . Practical rapid quenching instrument for the study of reaction mechanisms by electron paramagnetic resonance spectroscopy . Analytical Chemistry . 46 . 9 . 1248–1253 . 1974 . 10.1021/ac60345a034.
- Ballou DP, Entsch B, Cole LJ . Dynamics involved in catalysis by single-component and two-component flavin-dependent aromatic hydroxylases . Biochem. Biophys. Res. Commun. . 338 . 1 . 590–598 . 2005 . 16236251 . 10.1016/j.bbrc.2005.09.081.
- Gassner GT, Ludwig ML, Gatti DL, Correll CC, Ballou DP . Structure and mechanism of the iron-sulfur flavoprotein phthalate dioxygenase reductase . FASEB Journal . 9 . 14 . 1411–1418 . 1995 . 7589982. 10.1096/fasebj.9.14.7589982 . free . 2027.42/154520 . 14787031 . free .
- Web site: DP Ballou at Pubmed . 2013-10-31 .
- Web site: AAAS Welcomes Two from Medical School . 2013-10-27 . https://web.archive.org/web/20131019164603/http://www.medicineatmichigan.org/magazine/2007/spring/limelight/AAASwelcome.asp . 2013-10-19 . dead .
- Martin Bader, Wilson Muse, David P Ballou, Christian Gassner, James C.A Bardwell, "Oxidative Protein Folding Is Driven by the Electron Transport System", published in Cell Volume 98, Issue 2, p217–227, 23 July 1999
- Web site: Google Scholar.
