Dapiglutide Explained

Drug Name:Dapiglutide
Synonyms:ZP 7570
Legal Status:Investigational
Cas Number:2296814-85-0
Unii:J43GMI6IYW
C:192
H:302
N:46
O:57

Dapiglutide (formerly ZP 7570) is a dual GLP-1 and GLP-2 receptor agonist developed by Zealand Pharma.[1] [2]

Notes and References

  1. Reiner . Johannes . Berlin . Peggy . Held . Jascha . Thiery . Johanna . Skarbaliene . Jolanta . Griffin . Jonathan . Russell . Wayne . Eriksson . Per-Olof . Berner-Hansen . Mark . Ehlers . Luise . Vollmar . Brigitte . Jaster . Robert . Witte . Maria . Lamprecht . Georg . 2. Dapiglutide, a novel dual GLP-1 and GLP-2 receptor agonist, attenuates intestinal insufficiency in a murine model of short bowel . Journal of Parenteral and Enteral Nutrition . July 2022 . 46 . 5 . 1107–1118 . 10.1002/jpen.2286. free . 34705281 .
  2. Olsen . Minna B. . HöVelmann . Ulrike . Griffin . Jon . Knudsen . Kim M. . Eriksson . Per-Olof . Agersnap . Mikkel A. . 2. 335-OR: Dapiglutide, a Once-Weekly GLP-1R/GLP-2R Dual Agonist, Was Safe and Well Tolerated and Showed Dose-Dependent Body Weight Loss over Four Weeks in Healthy Subjects . Diabetes . 1 June 2022 . 71 . Supplement_1 . 10.2337/db22-335-OR. 249256542 .