Danube–Tisza Interfluve is the landscape in Hungarian territory (Hungary and Vojvodina (Vajdaság) in Serbia) in the Pannonian Basin between the Danube and Tisza rivers, east of Transdanubia. It covers a large part of the Great Hungarian Plain.
Its borders are Danube (west), Tisza (east), and Fruška Gora (Tarcal Mountain) (south). Its northeastern border is Rétköz small-landscape in Szabolcs-Szatmár-Bereg county.
The largest green area is the Kiskunság National Park. Avocets, geese and black-winged stilts nest in the area. The lakes provide a temporary home for tens of thousands of migratory birds. This ornithologist paradise is also a UNESCO biosphere reserve. Lake Szelid near Kalocsa, Lake Vadkert by Soltvadkert, Lake Kunfehér and Lake Sós at Kiskunhalas are ideal spots for bathing and camping.