DTaP-IPV vaccine explained

Type:combo
Component1:DTaP vaccine
Class1:Vaccine
Component2:Inactivated poliovirus vaccine
Class2:Vaccine
Tradename:Kinrix, Quadracel, Boostrix-IPV, Infanrix-IPV, others
Pregnancy Au:A
Legal Status:Rx-only
Routes Of Administration:Intramuscular injection
Cas Number:1688606-07-6
Atc Prefix:J07
Atc Suffix:CA02
Synonyms:diphtheria, tetanus, pertussis (acellular, component) and poliomyelitis (inactivated) vaccine (adsorbed, reduced antigen(s) content)

DTaP-IPV vaccine is a combination vaccine whose full generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed and inactivated poliovirus vaccine (IPV).[1] [2]

It is also known as DTaP/IPV, dTaP/IPV, DTPa-IPV, or DPT-IPV.[1] It protects against the infectious diseases diphtheria, tetanus, pertussis, and poliomyelitis.[1]

Branded formulations marketed in the USA are Kinrix from GlaxoSmithKline[3] and Quadracel from Sanofi Pasteur.[4]

Repevax is available in the UK.[5] [6]

Within Japan, the formulation is called 四種混合(shishukongou - "mixture of 4").Astellas markets it under the クアトロバック ('Quattro-back') formulation, while another is available from Mitsubishi Tanabe Pharma named テトラビック ('Tetrabic').[7] [8] A previous product by Takeda Pharmaceutical Company has been withdrawn by the company.[9]

Notes and References

  1. Web site: Diphtheria, Tetanus, Pertussis (Acellular, Component) And Poliomyelitis (Inactivated) Vaccine (Adsorbed). 15 July 2018. Drugs.com.
  2. Syed YY . DTaP-IPV-HepB-Hib Vaccine (Hexyon®): An Updated Review of its Use in Primary and Booster Vaccination . Paediatric Drugs . 21 . 5 . 397–408 . October 2019 . 31444785 . 6794236 . 10.1007/s40272-019-00353-7 .
  3. Web site: Kinrix. US Food and Drug Administration. 15 July 2018.
  4. Web site: Quadracel. US Food and Drug Administration. 15 July 2018.
  5. Web site: Repevax, suspension for injection, in pre-filled syringe - Summary of Product Characteristics (SmPC) - (emc) . www.medicines.org.uk . 31 December 2020.
  6. Book: British National Formulary (BNF). September 2020 – March 2021. BMJ Group and the Pharmaceutical Press. 978-0-85711-369-6. 80. 1381. 14. Vaccines.
  7. Web site: 医療用医薬品 : テトラビック (テトラビック皮下注シリンジ). 2021-02-27. www.kegg.jp.
  8. Web site: 医療用医薬品 : クアトロバック (クアトロバック皮下注シリンジ). 2021-02-27. www.kegg.jp.
  9. Web site: 【武田薬品】4種混合ワクチンの開発中止-ノロウイルスなどに資源投入|薬事日報ウェブサイト. 9 February 2015 . 2021-02-27.