DTP-HepB vaccine explained

DTP-HepB vaccine is a combination vaccine whose generic name is diphtheria and tetanus toxoids and whole-cell pertussis and hepatitis B (recombinant) vaccine (adsorbed) or DTP-Hep B. It protects against the infectious diseases diphtheria, tetanus, pertussis, and hepatitis B.[1]

A branded formulation, Tritanrix-HepB manufactured by GlaxoSmithKline, was granted marketing approval in the EU in 1996. Marketing approval lapsed in 2014.[2]

A review conducted in 2012 concluded that there was insufficient evidence to determine differences in safety and efficacy between DTP-HepB vaccine and Hib vaccine administered separately and pentavalent DTP-HepB-Hib vaccine.[3]

Notes and References

  1. Book: World Health Organization . World Health Organization Department of Immunization, Vaccines and Biologicals . Immunization in Practice: A Practical Guide for Health Staff . 2004 . World Health Organization . 9789241546515 . 18 . 15 July 2018 . en.
  2. Web site: Tritanrix HepB. European Medicines Agency. 14 July 2018. 15 July 2018. https://web.archive.org/web/20180715011003/http://www.ema.europa.eu/ema/pages/medicines/human/medicines/000093/human_med_001108.jsp. dead.
  3. Bar-On ES, Goldberg E, Hellmann S, Leibovici L . Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB) . The Cochrane Database of Systematic Reviews . 4 . 4 . CD005530 . April 2012 . 22513932 . 10.1002/14651858.CD005530.pub3 .

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