DTDP-L-rhamnose 4-epimerase explained

DTDP-L-rhamnose 4-epimerase
Ec Number:	5.1.3.25

DTDP-L-rhamnose 4-epimerase (dTDP-4-L-rhamnose 4-epimerase, wbiB (gene)) is an enzyme with systematic name dTDP-6-deoxy-beta-L-talose 4-epimerase.^[1] This enzyme catalyses the following chemical reaction

dTDP-6-deoxy-beta-L-talose

\rightleftharpoons

dTDP-6-deoxy-beta-L-mannose

The equilibrium is strongly towards dTDP-6-deoxy-beta-L-mannose.

Notes and References

Yoo HG, Kwon SY, Karki S, Kwon HJ . A new route to dTDP-6-deoxy-l-talose and dTDP-L-rhamnose: dTDP-L-rhamnose 4-epimerase in Burkholderia thailandensis . Bioorganic & Medicinal Chemistry Letters . 21 . 13 . 3914–7 . July 2011 . 21640586 . 10.1016/j.bmcl.2011.05.030 .