DTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase explained

DTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase
Ec Number:	2.3.1.210

DTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase (TDP-fucosamine acetyltransferase, WECD, RFFC) is an enzyme with systematic name acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-galactose N-acetyltransferase.^[1] This enzyme catalyses the following chemical reaction

acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose

\rightleftharpoons CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose

TDP-4-acetamido-4,6-dideoxy-D-galactose takes part in the biosynthesis of enterobacterial common antigen.

Notes and References

1. Hung MN, Rangarajan E, Munger C, Nadeau G, Sulea T, Matte A . Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis . Journal of Bacteriology . 188 . 15 . 5606–17 . August 2006 . 16855251 . 1540030 . 10.1128/jb.00306-06 .