DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase explained

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase
Ec Number:2.6.1.90

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase (dTDP-6-deoxy-D-xylohex-3-uloseaminase, FdtB, TDP-3-keto-6-deoxy-D-galactose-3-aminotransferase, RavAMT, TDP-3-keto-6-deoxy-D-galactose 3-aminotransferase, TDP-3-dehydro-6-deoxy-D-galactose 3-aminotransferase) is an enzyme with systematic name dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose:2-oxoglutarate aminotransferase.[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons

dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-glutamate

This enzyme is a pyridoxal-phosphate protein.

Notes and References

  1. Pfoestl A, Hofinger A, Kosma P, Messner P . Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T . The Journal of Biological Chemistry . 278 . 29 . 26410–7 . July 2003 . 12740380 . 10.1074/jbc.m300858200 . free .