DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase explained

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Ec Number:	2.3.1.197

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase (FdtC, dTDP-D-Fucp3N acetylase) is an enzyme with systematic name acetyl-CoA:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase.^[1] This enzyme catalyses the following chemical reaction

acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose

\rightleftharpoons CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose

dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose is a component of the glycan chain of the crystalline bacterial cell surface layer protein of Aneurinibacillus thermoaerophilus.

Notes and References

1. Pfoestl A, Hofinger A, Kosma P, Messner P . Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T . The Journal of Biological Chemistry . 278 . 29 . 26410–7 . July 2003 . 12740380 . 10.1074/jbc.m300858200 . free .