DPYSL3 explained

Dihydropyrimidinase-related protein 3 is an enzyme that in humans is encoded by the DPYSL3 gene.^{[1] [2] [3]} A recent bioinformatics study suggested that the DPYSL3 gene might have a prognostic role in neuroblastoma.^[4]

Further reading

• Dawson SJ, White LA . Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin . The Journal of Infection . 24 . 3 . 317–320 . May 1992 . 1602151 . 10.1016/S0163-4453(05)80037-4 .
• Inagaki H, Kato Y, Hamajima N, Nonaka M, Sasaki M, Eimoto T . Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system . Histochemistry and Cell Biology . 113 . 1 . 37–41 . January 2000 . 10664068 . 10.1007/s004180050005 . 11121195 .
• Matsuo T, Stauffer JK, Walker RL, Meltzer P, Thiele CJ . Structure and promoter analysis of the human unc-33-like phosphoprotein gene. E-box required for maximal expression in neuroblastoma and myoblasts . The Journal of Biological Chemistry . 275 . 22 . 16560–16568 . June 2000 . 10748015 . 10.1074/jbc.M001312200 . free .
• Fukada M, Watakabe I, Yuasa-Kawada J, Kawachi H, Kuroiwa A, Matsuda Y, Noda M . Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family . The Journal of Biological Chemistry . 275 . 48 . 37957–37965 . December 2000 . 10956643 . 10.1074/jbc.M003277200 . free .
• Book: Weitzdoerfer R, Fountoulakis M, Lubec G . Protein Expression in Down Syndrome Brain . Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down Syndrome brain . Journal of Neural Transmission. Supplementum . 2001 . 61 . 95–107 . 11771764 . 10.1007/978-3-7091-6262-0_8. 978-3-211-83704-7 .
• Franken S, Junghans U, Rosslenbroich V, Baader SL, Hoffmann R, Gieselmann V, Viebahn C, Kappler J . 6 . Collapsin response mediator proteins of neonatal rat brain interact with chondroitin sulfate . The Journal of Biological Chemistry . 278 . 5 . 3241–3250 . January 2003 . 12444086 . 10.1074/jbc.M210181200 . free .
• Rosslenbroich V, Dai L, Franken S, Gehrke M, Junghans U, Gieselmann V, Kappler J . Subcellular localization of collapsin response mediator proteins to lipid rafts . Biochemical and Biophysical Research Communications . 305 . 2 . 392–399 . May 2003 . 12745088 . 10.1016/S0006-291X(03)00754-X .
• Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP . Phosphoproteomic analysis of the developing mouse brain . Molecular & Cellular Proteomics . 3 . 11 . 1093–1101 . November 2004 . 15345747 . 10.1074/mcp.M400085-MCP200 . free .
• Choi YL, Kim CJ, Matsuo T, Gaetano C, Falconi R, Suh YL, Kim SH, Shin YK, Park SH, Chi JG, Thiele CJ . 6 . HUlip, a human homologue of unc-33-like phosphoprotein of Caenorhabditis elegans; Immunohistochemical localization in the developing human brain and patterns of expression in nervous system tumors . Journal of Neuro-Oncology . 73 . 1 . 19–27 . May 2005 . 15933812 . 10.1007/s11060-004-3013-3 . 25655752 .
• Cole AR, Causeret F, Yadirgi G, Hastie CJ, McLauchlan H, McManus EJ, Hernández F, Eickholt BJ, Nikolic M, Sutherland C . 6 . Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo . The Journal of Biological Chemistry . 281 . 24 . 16591–16598 . June 2006 . 16611631 . 1805471 . 10.1074/jbc.M513344200 . free .
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–648 . November 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
• Chicco D, Sanavia T, Jurman G . Signature literature review reveals AHCY, DPYSL3, and NME1 as the most recurrent prognostic genes for neuroblastoma . BioData Mining . 16 . 1 . 7 . March 2023 . 36870971 . 9985261 . 10.1186/s13040-023-00325-1 . 1756-0381 . free .

Notes and References

1. Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M, Nonaka M . A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution . Gene . 180 . 1–2 . 157–163 . November 1996 . 8973361 . 10.1016/S0378-1119(96)00445-3 .
2. Gaetano C, Matsuo T, Thiele CJ . Identification and characterization of a retinoic acid-regulated human homologue of the unc-33-like phosphoprotein gene (hUlip) from neuroblastoma cells . The Journal of Biological Chemistry . 272 . 18 . 12195–12201 . May 1997 . 9115293 . 10.1074/jbc.272.18.12195 . free .
3. Web site: Entrez Gene: DPYSL3 dihydropyrimidinase-like 3.
4. Chicco D, Sanavia T, Jurman G . Signature literature review reveals AHCY, DPYSL3, and NME1 as the most recurrent prognostic genes for neuroblastoma . BioData Mining . 16 . 1 . 7 . March 2023 . 36870971 . 9985261 . 10.1186/s13040-023-00325-1 . 1756-0381 . free .