DOTAM explained

DOTAM (also known as TCMC) is an organic compound used as a chelator much like its carboxylic acid analog DOTA. A derivative with a reactive linking group of para-isothiocyanatobenzyl attached to the cyclen ring is also of interest as a bifunctional chelator (BFC).[1] [2]

Notes and References

  1. Brennecke. Benjamin. Wang. Qinghua. Haap. Wolfgang. Grether. Uwe. Hu. Hai-Yu. Nazaré. Marc. 2021-04-21. DOTAM-Based, Targeted, Activatable Fluorescent Probes for the Highly Sensitive and Selective Detection of Cancer Cells. Bioconjugate Chemistry. en. 32. 4. 702–712. 10.1021/acs.bioconjchem.0c00699. 33691062. 232192471. 1043-1802.
  2. Stenberg. Vilde Yuli. Larsen. Roy Hartvig. Ma. Li-Wei. Peng. Qian. Juzenas. Petras. Bruland. Øyvind Sverre. Juzeniene. Asta. January 2021. Evaluation of the PSMA-Binding Ligand 212Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer. International Journal of Molecular Sciences. en. 22. 9. 4815. 10.3390/ijms22094815. 8124365. 34062920. free.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "DOTAM".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.