DOK3 explained

Docking protein 3 is a protein that in humans is encoded by the DOK3 gene.^{[1] [2] [3]}

Further reading

• Cong F, Yuan B, Goff SP . Characterization of a Novel Member of the DOK Family That Binds and Modulates Abl Signaling . Mol. Cell. Biol. . 19 . 12 . 8314–25 . 2000 . 10567556 . 10.1128/MCB.19.12.8314. 84915 .
• Grimm J . Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation . J. Cell Biol. . 154 . 2 . 345–54 . 2001 . 11470823 . 10.1083/jcb.200102032 . 2150770 . Sachs M . Britsch S . Di Cesare . S . Schwarz-Romond . T . Alitalo . K . Birchmeier . W .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . Feingold EA . Grouse LH . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Ota T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . Suzuki Y . Nishikawa T . Otsuki . Tetsuji . Sugiyama . Tomoyasu . Irie . Ryotaro . Wakamatsu . Ai . Hayashi . Koji . Sato . Hiroyuki . free .
• Robson JD, Davidson D, Veillette A . Inhibition of the Jun N-Terminal Protein Kinase Pathway by SHIP-1, a Lipid Phosphatase That Interacts with the Adaptor Molecule Dok-3 . Mol. Cell. Biol. . 24 . 6 . 2332–43 . 2004 . 14993273 . 10.1128/MCB.24.6.2332-2343.2004 . 355862 .
• Gerhard DS . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . Wagner L . Feingold EA . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Honma M . Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases . Genes Cells . 11 . 2 . 143–51 . 2007 . 16436051 . 10.1111/j.1365-2443.2006.00926.x . Higuchi O . Shirakata M . Yasuda . Tomoharu . Shibuya . Hiroshi . Iemura . Shun-Ichiro . Natsume . Tohru . Yamanashi . Yuji . 42571721 . free .

Notes and References

1. Lemay S, Davidson D, Latour S, Veillette A . Dok-3, a Novel Adapter Molecule Involved in the Negative Regulation of Immunoreceptor Signaling . Mol Cell Biol . 20 . 8 . 2743–54 . Apr 2000 . 10733577 . 85490 . 10.1128/MCB.20.8.2743-2754.2000 .
2. Favre C, Gerard A, Clauzier E, Pontarotti P, Olive D, Nunes JA . DOK4 and DOK5: new Dok-related genes expressed in human T cells . Genes Immun . 4 . 1 . 40–5 . Feb 2003 . 12595900 . 10.1038/sj.gene.6363891 . 24417010 .
3. Web site: Entrez Gene: DOK3 docking protein 3.