DNASE1L2 explained

Deoxyribonuclease-1-like 2 is an enzyme that in humans is encoded by the DNASE1L2 gene.^{[1] [2] [3]}

Further reading

• Jäger K, Fischer H, Tschachler E, Eckhart L . Terminal differentiation of nail matrix keratinocytes involves up-regulation of DNase1L2 but is independent of caspase-14 expression. . Differentiation . 75 . 10 . 939–46 . 2008 . 17490414 . 10.1111/j.1432-0436.2007.00183.x .
• Fischer H, Eckhart L, Mildner M . DNase1L2 degrades nuclear DNA during corneocyte formation. . J. Invest. Dermatol. . 127 . 1 . 24–30 . 2007 . 16902420 . 10.1038/sj.jid.5700503 . etal. free .
• Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Shiokawa D, Matsushita T, Kobayashi T . Characterization of the human DNAS1L2 gene and the molecular mechanism for its transcriptional activation induced by inflammatory cytokines . Genomics . 84 . 1 . 95–105 . 2005 . 15203207 . 10.1016/j.ygeno.2004.02.003 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Shiokawa D, Tanuma S . Characterization of human DNase I family endonucleases and activation of DNase gamma during apoptosis . Biochemistry . 40 . 1 . 143–52 . 2001 . 11141064 . 10.1021/bi001041a .

Notes and References

1. Rodriguez AM, Rodin D, Nomura H, Morton CC, Weremowicz S, Schneider MC . Identification, localization, and expression of two novel human genes similar to deoxyribonuclease I . Genomics . 42 . 3 . 507–13 . Sep 1997 . 9205125 . 10.1006/geno.1997.4748 .
2. Germino GG, Weinstat-Saslow D, Himmelbauer H, Gillespie GA, Somlo S, Wirth B, Barton N, Harris KL, Frischauf AM, Reeders ST . The gene for autosomal dominant polycystic kidney disease lies in a 750-kb CpG-rich region . Genomics . 13 . 1 . 144–51 . Jun 1992 . 1577479 . 10.1016/0888-7543(92)90214-D .
3. Web site: Entrez Gene: DNASE1L2 deoxyribonuclease I-like 2.