DCP1B explained

mRNA-decapping enzyme 1B is a protein that in humans is encoded by the DCP1B gene.^{[1] [2] [3]}

DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002).[supplied by OMIM]

Further reading

• Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP . A probability-based approach for high-throughput protein phosphorylation analysis and site localization . Nature Biotechnology . 24 . 10 . 1285–1292 . October 2006 . 16964243 . 10.1038/nbt1240 . vanc . 14294292 .
• Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ . 6 . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells . Nature Biotechnology . 23 . 1 . 94–101 . January 2005 . 15592455 . 10.1038/nbt1046 . vanc . 7200157 .
• Lehner B, Sanderson CM . A protein interaction framework for human mRNA degradation . Genome Research . 14 . 7 . 1315–1323 . July 2004 . 15231747 . 442147 . 10.1101/gr.2122004 .

Notes and References

1. Lykke-Andersen J . Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay . Molecular and Cellular Biology . 22 . 23 . 8114–8121 . December 2002 . 12417715 . 134073 . 10.1128/MCB.22.23.8114-8121.2002 .
2. Cougot N, Babajko S, Séraphin B . Cytoplasmic foci are sites of mRNA decay in human cells . The Journal of Cell Biology . 165 . 1 . 31–40 . April 2004 . 15067023 . 2172085 . 10.1083/jcb.200309008 .
3. Web site: Entrez Gene: DCP1B DCP1 decapping enzyme homolog B (S. cerevisiae).