Donald Henderson Explained
Donald Ainslie Henderson (September 7, 1928 – August 19, 2016) was an American physician, educator, and epidemiologist who directed a 10-year international effort (1967–1977) that eradicated smallpox throughout the world and launched international childhood vaccination programs.[1] From 1977 to 1990, he was Dean of the Johns Hopkins School of Public Health.[2] Later, he played a leading role in instigating national programs for public health preparedness and response following biological attacks and national disasters.[3] At the time of his death, he was Professor and Dean Emeritus of the Johns Hopkins Bloomberg School of Public Health, and Professor of Medicine and Public Health at the University of Pittsburgh, as well as Distinguished Scholar at the UPMC Center for Health Security.[4] [5] [6]
Early life and education
Henderson was born in Ohio.[7] His father, David Henderson, was an engineer; his mother, Eleanor McMillan, was a nurse. His interest in medicine was inspired by a Canadian uncle, William McMillan, who was a general practitioner and senior member of the Canadian House of Commons.[8]
Henderson graduated from Oberlin College in 1950 and received his MD from the University of Rochester School of Medicine in 1954. He was a resident physician in medicine at the Mary Imogene Bassett Hospital in Cooperstown, New York, and, later, a Public Health Service Officer in the Epidemic Intelligence Service of the Communicable Disease Center (now the Centers for Disease Control and Prevention—CDC). He earned an MPH degree in 1960 from the Johns Hopkins School of Hygiene and Public Health (now the Johns Hopkins Bloomberg School of Public Health).
Research and career
Eradication of smallpox
Henderson served as Chief of the CDC virus disease surveillance programs from 1960 to 1965, working closely with epidemiologist Alexander Langmuir. During this period, he and his unit developed a proposal for a United States Agency for International Development (USAID) program to eliminate smallpox and control measles during a 5-year period in 18 contiguous countries in western and central Africa.[9] This project was funded by USAID, with field operations beginning in 1967.
The USAID initiative provided an important impetus to a World Health Organization (WHO) program to eradicate smallpox throughout the world within a 10-year period. In 1966, Henderson moved to Geneva to become director of the campaign. At that time, smallpox was occurring widely throughout Brazil and in 30 countries in Africa and South Asia. More than 10 million cases and 2 million deaths were occurring annually. Vaccination brought some control, but the key strategy was "surveillance-containment". This technique entailed rapid reporting of cases from all health units and prompt vaccination of household members and close contacts of confirmed cases. WHO staff and advisors from some 73 countries worked closely with national staff. The last case occurred in Somalia on October 26, 1977, only 10 years after the program began. Three years later, the World Health Assembly recommended that smallpox vaccination could cease. Smallpox is the first human disease ever to be eradicated.[10] This success gave impetus to WHO's global Expanded Program on Immunization, which targeted other vaccine-preventable diseases, including poliomyelitis, measles, tetanus, diphtheria, and whooping cough.[11] Now targeted for eradication are poliomyelitis and Guinea Worm disease; after 25 years, this objective is close to being achieved.[12]
Later work
From 1977 through August 1990, Henderson was Dean of the Johns Hopkins School of Public Health. After being awarded the 1986 National Medal of Science by Ronald Reagan for his work leading the World Health Organization (WHO) smallpox eradication campaign, Henderson launched a public struggle to reverse the Reagan administration's decision to default on WHO payments.[13] In 1991, he was appointed associate director for life sciences, Office of Science and Technology Policy, Executive Office of the President (1991–93) and, later, deputy assistant secretary and senior science advisor in the Department of Health and Human Services (HHS). In 1998, he became the founding director of the Johns Hopkins Center for Civilian Biodefense Strategies, now the Johns Hopkins Center for Health Security.
Following the September 11, 2001, attack on the World Trade Center, HHS Secretary Tommy G. Thompson asked Henderson to assume responsibility for the Office of Public Health Preparedness (later the Office of the Assistant Secretary for Preparedness and Response).[14] [15] [16] For this purpose, $3 billion was appropriated by Congress.
In 2006, Henderson published an academic paper critical of social distancing as a pandemic measure, saying it would "result in significant disruption of the social functioning of communities and result in possibly serious economic problems".[17] [18]
At the time of his death, he served as the Editor Emeritus of the academic journal Health Security (formerly Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science).
Honors and awards
- 1975 – George McDonald Medal, London School of Tropical Medicine[19]
- 1978 – Public Welfare Medal, National Academy of Sciences[20]
- 1985 – Albert Schweitzer International Prize for Medicine
- 1986 – National Medal of Science in Biology[21]
- 1988 – The Japan Prize, shared with Isao Arita and Frank Fenner[22]
- 1990 – Health for All Medal, World Health Organization
- 1994 – Albert B. Sabin Gold Medal, Sabin Foundation[23]
- 1995 – John Stearns Medal, New York Academy of Medicine[24]
- 1996 – Edward Jenner Medal, Royal Society of Medicine[25]
- 2001 – Clan Henderson Society, Chiefs Order[26]
- 2002 – Presidential Medal of Freedom[27] [28]
- 2007 – John Snow Society's Pumphandle Lecture[29]
- 2013 – Order of Brilliant Star, with Grand Cordon, Republic of China[30] [31]
- 2014 – Prince Mahidol Award, Thailand[32] [33]
- 2015 – Charles Merieux Award, National Foundation for Infectious Diseases[34]
Seventeen universities conferred honorary degrees on Henderson.
Selected publications
- Fenner F, Henderson DA, Arita I, Jezek Z, Ladnyi. (1988) Smallpox and Its Eradication, Geneva, World Health Organization. The definitive archival history of smallpox.
- Henderson DA. (2009) Smallpox, the Death of a Disease New York: Prometheus Books
- Henderson DA (1993) Surveillance systems and intergovernmental cooperation. In: Morse SS, ed. Emerging Viruses. New York: Oxford University Press: 283–289.
- Henderson DA, Borio LL (2005) Bioterrorism: an overview. In Principles and Practice of Infectious Diseases (Eds. Mandell MD, Bennett JE, Dolin R) Phil, Churchill Livingstone, 3591–3601.
- Henderson DA (2010) The global eradication of smallpox: Historical Perspective and Future Prospects in The Global Eradication of Smallpox (Ed: Bhattacharya S, Messenger S) Orient Black Swan, London. 7–35
- Henderson DA, Shelokov A . 1959 . Medical progress: Epidemic neuromyasthenia—clinical syndrome . The New England Journal of Medicine. 260 . 15 . 757–764, 814–818 . 10.1056/NEJM195904092601506. 13644582 .
- Langmuir AD, Henderson DA, Serfling RE . 1964 . The epidemiological basis for the control of influenza . American Journal of Public Health and the Nation's Health. 54 . 4. 563–571 . 10.2105/ajph.54.4.563. 14136320 . 1254817.
- Neff JM, Lane JM, Pert JH, Moore R, Millar JD, Henderson DA . 1967 . Complications of smallpox vaccination: I. National survey in the United States, 1963 . The New England Journal of Medicine. 276 . 3. 125–132 . 10.1056/nejm196701192760301 . 4381041.
- Henderson DA. (1967) Smallpox eradication and measles-control programs in West and Central Africa: Theoretical and practical approaches and problems. Industry and Trop Health VI, 112–120, Harvard School of Public Health, Boston.
- Henderson DA . 1972 . Epidemiology in the global eradication of smallpox . International Journal of Epidemiology. 1 . 1. 25–30 . 10.1093/ije/1.1.25 . 4669176.
- Henderson DA . 1975 . Smallpox eradication—the final battle (Jenner Lecture) . Journal of Clinical Pathology. 28 . 11. 843–849 . 10.1136/jcp.28.11.843. 802231 . 475879.
- Henderson DA . 1976 . The eradication of smallpox . Scientific American . 235 . 4. 25–33 . 10.1038/scientificamerican1076-25. 788150 . 1976SciAm.235d..25H .
- Henderson DA . 1998 . The challenge of eradication: lessons from past eradication campaigns (The Pittsfield Lecture) . The International Journal of Tuberculosis and Lung Disease . 2 . 54–58.
- .
- Henderson . DA . 1999 . The looming threat of bioterrorism . Science . 283 . 5406 . 1279–82 . 10.1126/science.283.5406.1279. 10037590 . 1999Sci...283.1279. . 10.1.1.597.8970 .
- Henderson . DA . Inglesby . TV . Barlett . JG . 1999 . Smallpox as a biological weapon: medical and public health management . JAMA . 281 . 22 . 2127–37 . 10.1001/jama.281.22.2127 . 10367824 . etal.
- O'Toole . T . Henderson . DA . 2001 . A clearly present danger: confronting the threat of bioterrorism . Harvard International Forum . 23 . 49–53.
Personal life
Henderson married Nana Irene Bragg in 1951. The couple had a daughter and two sons, whom they raised in Atlanta, Georgia and Geneva, Switzerland. He died at Gilchrist Hospice, Towson, Maryland, at the age of 87, after fracturing his hip.[35]
Notes and References
- Paul . Paul Sinha . Sinha . . . Episode 1 (season 3). 15 June 2017 . 20 June 2017 . Radio Broadcast . 1 .
- http://www.jhsph.edu/about/history/deans-of-the-school/ Deans of the Bloomberg School. Johns Hopkins Bloomberg School of Public Health. Retrieved September 16, 2015.
- http://www.cidrap.umn.edu/news-perspective/2001/11/d-henderson-direct-new-office-public-health-preparedness D. A. Henderson to Direct New Office of Public Health Preparedness
- Web site: Our Staff: D. A. Henderson, MD, MPH. UPMC Center for Health Security. 2015. Retrieved September 16, 2015, 2015. . October 20, 2015 . November 14, 2017 . https://web.archive.org/web/20171114133155/http://www.upmchealthsecurity.org/our-staff/profiles/henderson/index.html . dead .
- Donald Henderson – Faculty Directory | Johns Hopkins Bloomberg School of Public Health. Web site: Donald Henderson - Faculty Directory | Johns Hopkins Bloomberg School of Public Health . 2015-10-20 . dead . https://web.archive.org/web/20150914221242/http://www.jhsph.edu/faculty/directory/profile/3691/donald-henderson . 2015-09-14 . . Retrieved September 16, 2015.
- Breman. Joel . Donald Ainslie Henderson (1928–2016) Epidemiologist who led the effort to eradicate smallpox . Nature . 538. 7623 . 2016 . 42 . 10.1038/538042a . 27708300. free .
- News: Williams. John. D.A. Henderson, the former dean of Bloomberg School of Public Health credited with eradicating smallpox, dies. 21 August 2016 . Baltimore Sun . https://web.archive.org/web/20160824112023/https://www.baltimoresun.com/news/obituaries/bs-md-ob-da-henderson-20160820-story.html . 2016-08-24.
- Henderson, D.A. Smallpox: The Death of a Disease. Amherst, NY: Prometheus Books, 2009. p. 21.
- Henderson . D . Klepac . P . 2013 . Lessons from the Eradication of Smallpox: An Interview with D. A. Henderson . Philos Trans R Soc B . 368 . 1623. 20130113 . 10.1098/rstb.2013.0113. 23798700 . 3720050 .
- http://www.who.int/topics/smallpox/en/ Health Topics: Smallpox. World Health Organization. 2015. Retrieved September 16, 2015
- https://web.archive.org/web/20131208072315/http://www.who.int/immunization/programmes_systems/en/ Immunization, Vaccines and Biologicals: National Programmes and Systems. World Health Organization. 2015. Retrieved October 10, 2015.
- https://web.archive.org/web/20140326175756/http://www.who.int/immunization/programmes_systems/supply_chain/benefits_of_immunization/en/ Immunization, Vaccines and Biologicals: The Expanded Programme on Immunization. World Health Organization. 2015. Retrieved September 16, 2015.
- https://www.jhsph.edu/covid-19/articles/the-other-time-a-us-president-withhel-who-funds.html The Other Time a U.S. President Withheld WHO Funds. JHSPH. April 21, 2020. Retrieved April 22, 2020.
- http://www.cidrap.umn.edu/news-perspective/2001/11/d-henderson-direct-new-office-public-health-preparedness D. A. Henderson to Direct New Office of Public Health Preparedness. CIDRAP News. November 6, 2001. Retrieved September 16, 2015.
- https://www.hhs.gov/about/historical-highlights/index.html HHS Historical Highlights. US Department of Health and Human Services. 2014. Retrieved September 17, 2015.
- Statement of Tommy G. Thompson: Secretary, Department of Health and Human Services. US House of Representatives Committee on Energy and Commerce. Washington, DC: Assistant Secretary for Legislation, Department of Health and Human Services; 2015. Web site: Tommy G. Thompson, Secretary, HHS . 2017-09-09 . dead . https://web.archive.org/web/20161104042212/http://www.hhs.gov/asl/testify/t011115.html . 2016-11-04 . . Retrieved September 17, 2015.
- News: Lipton. Eric. Steinhauer. Jennifer. 2020-04-22. The Untold Story of the Birth of Social Distancing. en-US. The New York Times. 2021-11-05. 0362-4331.
- Web site: November 2006. Disease Mitigation Measures in the Control of Pandemic Influenza. 2021-11-05. DocumentCloud.
- Web site: Previous Medal Winners. Royal Society of Tropical Medicine and Hygiene. Retrieved August 24, 2015. . October 20, 2015 . January 23, 2017 . https://web.archive.org/web/20170123204106/http://rstmh.org/awards/previous-medal-winners . dead .
- http://www.nasonline.org/programs/awards/public-welfare-medal.html Public Welfare Medal. National Academy of Sciences. 2015. Retrieved August 24, 2015.
- https://www.nsf.gov/od/nms/recip_details.jsp?recip_id=165 The President's National Medal of Science: Recipient Details – Donald A. Henderson. National Science Foundation. Retrieved August 24, 2015.
- http://www.japanprize.jp/en/prize_past_1988_prize02.html Laureates of the Japan Prize: The 1988 (4th) Japan Prize. The Japan Prize Foundation. Retrieved August 24, 2015.
- Web site: jThe Albert B. Sabin Gold Medal Award. Sabin Vaccine Institute. 2014. August 24, 2015.
- http://www.nyam.org/fellows-members/awards.html#stearns Anniversary Discourse & Awards. The New York Academy of Medicine.
- Stanwell-Smith R . 1996 . Immunization: Celebrating the Past and Injecting the Future . J R Soc Med . 89 . 9. 509–513 . 1295915 . 8949520. 10.1177/014107689608900909 .
- Web site: The Chiefs Order. Clan Henderson Society. 2013.. https://web.archive.org/web/20161009002943/http://www.clanhendersonsociety.org/the-chiefs-order/. dead. October 9, 2016.
- https://georgewbush-whitehouse.archives.gov/news/releases/2002/06/20020620-16.html President Bush Announced the Recipients of the Presidential Medal of Freedom. White House Office of the Press Secretary. June 21, 2002. Retrieved August 24, 2015.
- https://www.nytimes.com/2002/07/09/politics/09CND-MEDA.html Bush Honors 12 with Presidential Medal of Freedom. The New York Times. July 9, 2002. Retrieved August 24, 2015
- Web site: 2007 D A Henderson: Polio Eradication, a reconsideration of strategy . The John Snow Society . 18 August 2024 . 9 September 2007.
- http://english.president.gov.tw/Default.aspx?tabid=491&itemid=30401&rmid=2355 President Ma Bestows Order of Brilliant Star with Grand Cordon on Professor Donald A. Henderson of University of Pittsburgh. Office of the President, Republic of China (Taiwan). July 4, 2013. Retrieved August 24, 2015.
- Web site: Republic of China (Taiwan) Honors D. A. Henderson. UPMC Center for Health Security. July 8, 2013. Retrieved August 24, 2015. . October 20, 2015 . March 4, 2016 . https://web.archive.org/web/20160304141805/http://www.upmchealthsecurity.org/about-the-center/pressroom/press_releases/2013-07-08_Henderson_Award.html . dead .
- Web site: Biography of Laureate. Prince Mahidol Award Foundation.. https://web.archive.org/web/20170103165439/http://www.princemahidolaward.org/laureate-bio.en.php?type=ind&id=2014-11-06%2015:26:17. dead. January 3, 2017.
- http://www.princemahidolaward.org/display-news.en.php?id=2014-11-06%2017:55:27 The Announcement for the Prince Mahidol Award 2014. Prince Mahidol Award Foundation. November 6, 2014.
- Web site: Dr. Charles Merieux Award for Achievement in Vaccinology and Immunology. National Foundation for Infectious Diseases. Retrieved August 24, 2015. . October 20, 2015 . June 6, 2017 . https://web.archive.org/web/20170606000510/http://www.nfid.org/awards/merieux . dead .
- Archives Reference: The Donald A. Henderson Collection in the Institute of the History of Medicine Library at Johns Hopkins spans his career in smallpox eradication, including newspaper articles, honors, biographical material, lecture notes, speeches, and correspondence as well as medals and other awards.