D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase explained

D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Ec Number:	3.1.3.82

D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphatase (EC 3.1.3.82) is an enzyme with systematic name D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphohydrolase.^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

D-glycero-β-D-manno-heptose 1,7-bisphosphate + H₂O

\rightleftharpoons
D-glycero-β-D-manno-heptose 1-phosphate + phosphate

The enzyme is involved in biosynthesis of ADP-L-glycero-β-D-manno-heptose.

Notes and References

1. Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P . Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli . Journal of Bacteriology . 184 . 2 . 363–9 . January 2002 . 11751812 . 139585 . 10.1128/jb.184.2.363-369.2002 .
2. Valvano MA, Messner P, Kosma P . Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides . Microbiology . 148 . Pt 7 . 1979–89 . July 2002 . 12101286 . 10.1099/00221287-148-7-1979 . free .
3. Wang L, Huang H, Nguyen HH, Allen KN, Mariano PS, Dunaway-Mariano D . Divergence of biochemical function in the HAD superfamily: D-glycero-β-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB) . Biochemistry . 49 . 6 . 1072–81 . February 2010 . 20050615 . 2844805 . 10.1021/bi902018y .