D-glycero-alpha-D-manno-heptose 1,7-bisphosphate 7-phosphatase explained

D-glycero-α-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Ec Number:3.1.3.83

D-glycero-α-D-manno-heptose 1,7-bisphosphate 7-phosphatase (EC 3.1.3.83) is an enzyme with systematic name D-glycero-α-D-manno-heptose 1,7-bisphosphate 7-phosphohydrolase.[1] This enzyme catalyses the following chemical reaction

D-glycero-α-D-manno-heptose 1,7-bisphosphate + H2O

\rightleftharpoons


D-glycero-α-D-manno-heptose 1-phosphate + phosphate

The enzyme is involved in biosynthesis of GDP-D-glycero-α-D-manno-heptose.

Notes and References

  1. Wang L, Huang H, Nguyen HH, Allen KN, Mariano PS, Dunaway-Mariano D . Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB) . Biochemistry . 49 . 6 . 1072–81 . February 2010 . 20050615 . 2844805 . 10.1021/bi902018y .