D-glycero-alpha-D-manno-heptose-7-phosphate kinase explained

D-glycero-alpha-D-manno-heptose-7-phosphate kinase
Ec Number:	2.7.1.168

D-glycero-alpha-D-manno-heptose-7-phosphate kinase (D-alpha-D-heptose-7-phosphate kinase, hdda (gene)) is an enzyme with systematic name ATP:D-glycero-alpha-D-manno-heptose 7-phosphate 1-phosphotransferase.^{[1] [2]} This enzyme catalyses the following chemical reaction

D-glycero-alpha-D-manno-heptose 7-phosphate + ATP

\rightleftharpoons D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + ADP

The enzyme participates in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose.

Notes and References

1. Kneidinger B, Graninger M, Puchberger M, Kosma P, Messner P . Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose . The Journal of Biological Chemistry . 276 . 24 . 20935–44 . June 2001 . 11279237 . 10.1074/jbc.m100378200 . free .
2. Valvano MA, Messner P, Kosma P . Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides . Microbiology . 148 . Pt 7 . 1979–89 . July 2002 . 12101286 . 10.1099/00221287-148-7-1979 . free .