D-arabitol-phosphate dehydrogenase explained

D-arabitol-phosphate dehydrogenase
Ec Number:	1.1.1.301

D-arabitol-phosphate dehydrogenase (APDH, D-arabitol 1-phosphate dehydrogenase, D-arabitol 5-phosphate dehydrogenase) is an enzyme with systematic name D-arabitol-phosphate:NAD⁺ oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

D-arabitol 1-phosphate + NAD⁺

\rightleftharpoons D-xylulose 5-phosphate + NADH + H⁺

This enzyme participates in arabitol catabolism. The enzyme also converts D-arabitol 5-phosphate to D-ribulose 5-phosphate at a lower rate.

Notes and References

1. Povelainen M, Eneyskaya EV, Kulminskaya AA, Ivanen DR, Kalkkinen N, Neustroev KN, Miasnikov AN . Biochemical and genetic characterization of a novel enzyme of pentitol metabolism: D-arabitol-phosphate dehydrogenase . The Biochemical Journal . 371 . Pt 1 . 191–7 . April 2003 . 12467497 . 1223252 . 10.1042/BJ20021096 .